La educación energética en la secundaria básica: una alternativa para su desarrollo/ Power-saving education in junior high school. An alternative for its development

The article approaches the need of given instruction on energy-saving as a constituent of a comprehensive education al high school. The aim is to describe a developmental strategy, devised on the basis of specially tailored theoretical framework, observation, questionnaires and interviews. The main finding is the proposal of an alternative to achieve educational objectives on this area.El artículo aborda la necesidad de la educación energética como parte de la formación integral de los estudiantes del nivel secundario. El objetivo fue la descripción de una estrategia para su desarrollo. Se emplearon los métodos teóricos del analítico-sintético, el inductivo-deductivo y el sistémico-estructural-funcional. Del nivel empírico se utilizaron la observación, la revisión documental, los cuestionarios y las entrevistas. El resultado fundamental del estudio es la propuesta de estrategia como alternativa para el desarrollo de la educación energética

Building Cultural Heritage Resilience through Remote Sensing: An Integrated Approach Using Multi-Temporal Site Monitoring, Datafication, and Web-GL Visualization

In the American West, wildfires and earthquakes are increasingly threatening the archaeological, historical, and tribal resources that define the collective identity and connection with the past for millions of Americans. The loss of said resources diminishes societal understanding of the role cultural heritage plays in shaping our present and future. This paper examines the viability of employing stationary and SLAM-based terrestrial laser scanning, close-range photogrammetry, automated surface change detection, GIS, and WebGL visualization techniques to enhance the preservation of cultural resources in California. Our datafication approach combines multi-temporal remote sensing monitoring of historic features with legacy data and collaborative visualization to document and evaluate how environmental threats affect built heritage. We tested our methodology in response to recent environmental threats from wildfire and earthquakes at Bodie, an iconic Gold Rush-era boom town located on the California and Nevada border. Our multi-scale results show that the proposed approach effectively integrates highly accurate 3D snapshots of Bodie’s historic buildings before/after disturbance, or post-restoration, with surface change detection and online collaborative visualization of 3D geospatial data to monitor and preserve important cultural resources at the site. This study concludes that the proposed workflow enhances the monitoring of at-risk California’s cultural heritage and makes a call to action to employ remote sensing as a pathway to advanced planning. View Full-Tex

La educación energética en la secundaria básica: una alternativa para su desarrollo /Power‐saving education in junior high school. An alternative for its development

The article approaches the need of given instruction on energy‐saving as a constituent of a comprehensive education al high school. The aim is to describe a developmental strategy, devised on the basis of specially tailored theoretical framework, observation, questionnaires and interviews. The main finding is the proposal of an alternative to achieve educational objectives on this area

Developing an interoperable cloud-based visualization workflow for 3D archaeological heritage data. The Palenque 3D Archaeological Atlas

In archaeology, 3D data has become ubiquitous, as researchers routinely capture high resolution photogrammetry and LiDAR models and engage in laborious 3D analysis and reconstruction projects at every scale: artifacts, buildings, and entire sites. The raw data and processed 3D models are rarely shared as their computational dependencies leave them unusable by other scholars. In this paper we outline a novel approach for cloud-based collaboration, visualization, analysis, contextualization, and archiving of multi-modal giga-resolution archaeological heritage 3D data. The Palenque 3D Archaeological Atlas builds on an open source WebGL systems that efficiently interlink, merge, present, and contextualize the Big Data collected at the ancient Maya city of Palenque, Mexico, allowing researchers and stakeholders to visualize, access, share, measure, compare, annotate, and repurpose massive complex archaeological datasets from their web-browsers

Planeamiento estratégico agregado de la macro región VII

El Plan Estratégico Agregado para la macro región siete, que está conformada por los departamentos de Ayacucho, Huancavelica e Ica, se ha realizado tomando en cuenta el modelo secuencial del Proceso Estratégico hecho por el Dr. Fernando D´Alessio, donde se plantean las estrategias que permitirán el crecimiento sostenible de los sectores económicos de la macro región, utilizando de manera eficiente los recursos naturales y planteando nuevas actividades económicas que permitirá el desarrollo socio-económico de su población, para ello se realizó un análisis de su situación actual, en la cual se determinó las fortalezas y debilidades así como sus oportunidades y amenazas. La macro región siete cuenta con las tres regiones naturales del país, lo que le otorga una ventaja comparativa con respecto a otras macro regiones y será explotada respetando la sostenibilidad de los recursos. Así, en el análisis elaborado, se está planteando el desarrollo del primer circuito turístico que integre a toda la macro región, para ello se incentivará el turismo vivencial y eco turismo, que permitirá a los pobladores de las zonas de influencia obtener ingresos por los servicios prestados a los visitantes. El Plan Estratégico de la macro región siete se basa en cuatro pilares fundamentales que permitirán su desarrollo y crecimiento, estos son: (a) la educación, su posición competitiva está ligeramente debajo del promedio nacional pero es muy factible de revertir a mediano plazo, (b) el turismo, para potenciarlo se mejoraran las redes viales de conexión, con la ayuda del sector privado, obras por impuestos, etc., (c) la agro exportación, que se potenciará con la reducción de costos logísticos, y (d) la utilización de energías renovables, para ello los objetivos de largo plazo planteados permitirán elevar la competitividad de la macro región siete convirtiéndola en el referente del paísThe Added Strategic Plan for the seven macro region, which is made up of the departments of Ayacucho, Huancavelica and Ica, has been made taking into account the sequential model of the Strategic Process by Dr. Fernando D'Alessio, where strategies arise that will enable sustainable growth of economic sectors of the macro region, efficiently using natural resources and raising new economic activities that will enable the socio-economic development of its people, to do an analysis of their current situation was conducted in which the strengths and weaknesses as well as its opportunities and threats was determined. The seven macro region has three natural regions of the country, which gives it a comparative advantage over other macro regions and will be exploited respecting the sustainability of resources. Thus, in the analysis prepared, it is considering the development of the first tourist circuit that integrates the entire macro region, for which the experiential tourism and ecotourism, which will allow the inhabitants of the areas of influence monetizing services will be encouraged provided to visitors. The Strategic Plan of the seven macro region is based on four pillars that allow development and growth, these are: (a) education, its competitive position is slightly below the national average but is very likely to reverse in the medium term, ( b) tourism, to enhance it road networks connecting improve, with the help of the private sector, tax works, etc., (c) agro export, which will be enhanced by reducing logistics costs, and (d) the use of renewable energies, for this long-term goals raised, will enable increase the competitiveness of the seven macro region making it the benchmark in the countryTesi

Normothermic regional perfusion vs. super-rapid recovery in controlled donation after circulatory death liver transplantation

[Background & Aims] Although there is increasing interest in its use, definitive evidence demonstrating a benefit for postmortem normothermic regional perfusion (NRP) in controlled donation after circulatory death (cDCD) liver transplantation is lacking. The aim of this study was to compare results of cDCD liver transplants performed with postmortem NRP vs. super-rapid recovery (SRR), the current standard for cDCD.[Methods] This was an observational cohort study including all cDCD liver transplants performed in Spain between June 2012 and December 2016, with follow-up ending in December 2017. Each donor hospital determined whether organ recovery was performed using NRP or SRR. The propensity scores technique based on the inverse probability of treatment weighting (IPTW) was used to balance covariates across study groups; logistic and Cox regression models were used for binary and time-to-event outcomes.[Results] During the study period, there were 95 cDCD liver transplants performed with postmortem NRP and 117 with SRR. The median donor age was 56 years (interquartile range 45–65 years). After IPTW analysis, baseline covariates were balanced, with all absolute standardised differences <0.15. IPTW-adjusted risks were significantly improved among NRP livers for overall biliary complications (odds ratio 0.14; 95% CI 0.06–0.35, p <0.001), ischaemic type biliary lesions (odds ratio 0.11; 95% CI 0.02–0.57; p = 0.008), and graft loss (hazard ratio 0.39; 95% CI 0.20–0.78; p = 0.008).[Conclusions] The use of postmortem NRP in cDCD liver transplantation appears to reduce postoperative biliary complications, ischaemic type biliary lesions and graft loss, and allows for the transplantation of livers even from cDCD donors of advanced age.[Lay summary] This is a propensity-matched nationwide observational cohort study performed using livers recovered from donors undergoing cardiac arrest provoked by the intentional withdrawal of life support (controlled donation after circulatory death, cDCD). Approximately half of the livers were recovered after a period of postmortem in situ normothermic regional perfusion, which restored warm oxygenated blood to the abdominal organs, whereas the remainder were recovered after rapid preservation with a cold solution. The study results suggest that the use of postmortem normothermic regional perfusion helps reduce rates of post-transplant biliary complications and graft loss and allows for the successful transplantation of livers from older cDCD donors.Peer reviewe

Diseño para el consumo cultural, la innovación y la inclusión social

Esta obra presenta diversos trabajos de investigación que tienen en común propuestas de diseño desde la cultura, la inclusión y la innovación social, desarrolladas por investigadores nacionales e internacionales adscritos a diversas universidades, así como a programas de posgrado

Search for dark matter produced in association with bottom or top quarks in √s = 13 TeV pp collisions with the ATLAS detector

A search for weakly interacting massive particle dark matter produced in association with bottom or top quarks is presented. Final states containing third-generation quarks and miss- ing transverse momentum are considered. The analysis uses 36.1 fb−1 of proton–proton collision data recorded by the ATLAS experiment at √s = 13 TeV in 2015 and 2016. No significant excess of events above the estimated backgrounds is observed. The results are in- terpreted in the framework of simplified models of spin-0 dark-matter mediators. For colour- neutral spin-0 mediators produced in association with top quarks and decaying into a pair of dark-matter particles, mediator masses below 50 GeV are excluded assuming a dark-matter candidate mass of 1 GeV and unitary couplings. For scalar and pseudoscalar mediators produced in association with bottom quarks, the search sets limits on the production cross- section of 300 times the predicted rate for mediators with masses between 10 and 50 GeV and assuming a dark-matter mass of 1 GeV and unitary coupling. Constraints on colour- charged scalar simplified models are also presented. Assuming a dark-matter particle mass of 35 GeV, mediator particles with mass below 1.1 TeV are excluded for couplings yielding a dark-matter relic density consistent with measurements

Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial

Background: Glucagon-like peptide 1 receptor agonists differ in chemical structure, duration of action, and in their effects on clinical outcomes. The cardiovascular effects of once-weekly albiglutide in type 2 diabetes are unknown. We aimed to determine the safety and efficacy of albiglutide in preventing cardiovascular death, myocardial infarction, or stroke. Methods: We did a double-blind, randomised, placebo-controlled trial in 610 sites across 28 countries. We randomly assigned patients aged 40 years and older with type 2 diabetes and cardiovascular disease (at a 1:1 ratio) to groups that either received a subcutaneous injection of albiglutide (30–50 mg, based on glycaemic response and tolerability) or of a matched volume of placebo once a week, in addition to their standard care. Investigators used an interactive voice or web response system to obtain treatment assignment, and patients and all study investigators were masked to their treatment allocation. We hypothesised that albiglutide would be non-inferior to placebo for the primary outcome of the first occurrence of cardiovascular death, myocardial infarction, or stroke, which was assessed in the intention-to-treat population. If non-inferiority was confirmed by an upper limit of the 95% CI for a hazard ratio of less than 1·30, closed testing for superiority was prespecified. This study is registered with ClinicalTrials.gov, number NCT02465515. Findings: Patients were screened between July 1, 2015, and Nov 24, 2016. 10 793 patients were screened and 9463 participants were enrolled and randomly assigned to groups: 4731 patients were assigned to receive albiglutide and 4732 patients to receive placebo. On Nov 8, 2017, it was determined that 611 primary endpoints and a median follow-up of at least 1·5 years had accrued, and participants returned for a final visit and discontinuation from study treatment; the last patient visit was on March 12, 2018. These 9463 patients, the intention-to-treat population, were evaluated for a median duration of 1·6 years and were assessed for the primary outcome. The primary composite outcome occurred in 338 (7%) of 4731 patients at an incidence rate of 4·6 events per 100 person-years in the albiglutide group and in 428 (9%) of 4732 patients at an incidence rate of 5·9 events per 100 person-years in the placebo group (hazard ratio 0·78, 95% CI 0·68–0·90), which indicated that albiglutide was superior to placebo (p&lt;0·0001 for non-inferiority; p=0·0006 for superiority). The incidence of acute pancreatitis (ten patients in the albiglutide group and seven patients in the placebo group), pancreatic cancer (six patients in the albiglutide group and five patients in the placebo group), medullary thyroid carcinoma (zero patients in both groups), and other serious adverse events did not differ between the two groups. There were three (&lt;1%) deaths in the placebo group that were assessed by investigators, who were masked to study drug assignment, to be treatment-related and two (&lt;1%) deaths in the albiglutide group. Interpretation: In patients with type 2 diabetes and cardiovascular disease, albiglutide was superior to placebo with respect to major adverse cardiovascular events. Evidence-based glucagon-like peptide 1 receptor agonists should therefore be considered as part of a comprehensive strategy to reduce the risk of cardiovascular events in patients with type 2 diabetes. Funding: GlaxoSmithKline

Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic

This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic